Whenever a breast cancer surgeon performs a lumpectomy, thereās always a lingering concern: Has enough surrounding tissue been removed to ensure that no malignant cells remain? Though surgeons have some tools to guide them, the only way to know for certain is for a pathologist to examine the margins, or edges, of the excised tumor following surgery. But thanks to a new device called MarginProbeĀ®, which detects electromagnetic differences between cells and normal breast tissue, surgeons can now get a more accurate assessment while they operate, sparing many women with early-stage breast cancer from .
NYU Langone was the first hospital in the tri-state area to use MarginProbeĀ®, and our physician-researchers were part of a pivotal study of over 600 women that led to its approval by the FDA. The results showed that MarginProbeĀ® was up to three times as effective in finding additional cancer on the margins of tumorous tissue as traditional methods, such as inspecting and imaging the tissue. Itās an advance that could benefit the more than 170,000 women who undergo a lumpectomy each year. āIn about 20 percent of cases, surgeons find that they have to reoperate to remove additional tissue,ā notes lead author , director of breast surgery at NYU Langoneās . āWe felt we could and should do better for our patients.ā
Re-excision surgery is frustrating and stressful for the patient, Dr. Schnabel explains, and it may delay necessary follow-up treatments like radiation and chemotherapy. An additional operation can also result in negative cosmetic effects. āMarginProbeĀ® is a major advance,ā says Dr. Schnabel, because doctors and patients alike can feel more confident that only one surgery will be necessary.